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I have been put on Synthroid about three months ago to treat my underactive thyroid. Before I tried Synthroid I had tried out several other meds but they were either not sufficiently effective for me or caused side effects I couldn't tolerate. In general I almost got used to feeling constant exhaustion, cold intolerance, and extreme tiredness. My skin was so horribly dry and I couldn't change this condition in any way. I used to buy tons of nourishing and moisturizing creams and rubbed it all over my body to get rid of those nasty sensations of itching, cracking and irritation. Besides I had severe problems with water retention. I needed to strictly control water intake in order to keep myself conscious. With Synthroid many of those problems disappeared completely. I feel so much better now that I can not actually believe it. Now I am working at the extra weight I have gained when concentrated on my search for a medication that would drive away the worst symptoms. I am sure with Synthroid I'll achieve good results and will bring the quality of my life to a much higher level.

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Severe allergic reactions (rash; hives; itching; difficulty breathing; flushing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); changes in appetite; changes in menstrual periods; chest pain; diarrhea; excessive sweating; fast or irregular heartbeat; fever; heat intolerance; joint pain; leg cramps; mental or mood changes (eg, anxiety, irritability, nervousness); muscle weakness; seizures; severe or persistent headache or fatigue; shortness of breath; stomach cramps; tremors; trouble sleeping; unusual weight gain or weight loss; vomiting; wheezing.

In teens, goiters are usually caused by the autoimmune thyroid conditions discussed above, which might show no obvious symptoms until the goiter is visible as a swelling at the front of the neck.

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He was diagnosed with CRF two years ago.

The 2007 ES guidelines recommended case finding targeted to specific groups of patients who are at an increased risk of developing hypothyroidism such as women with 1) a personal or family history of thyroid disease, 2) goiter, 3) positive thyroid antibodies, 4) symptoms or clinical signs suggesting thyroid dysfunction, 5) history of autoimmune disease or type 1diabetes mellitus, 6) infertility, 7) history of miscarriage or preterm delivery, and 8) a history of head and neck irradiation ().

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In this prospective, randomized trial, 984 unselected women were screened for TPOAb positivity and thyroid function tests during their first obstetrical appointment and were divided into 3 groups.

Another means of assessing whether the hypothyroidism will be permanent is to reduce the l-T 4 dosage by 50% for 30 days; if the serum TSH remains normal after this reduction, l-T 4 should be discontinued and thyroid function tests should be reevaluated subsequently to confirm maintenance of euthyroidism.

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When thyroid tests are done, they should always be done first thing in the morning when the metabolism is near its low point of the day.

In addition, if you are on thyroid medication, increase calcium supplementation to reduce the risk of bone loss.

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Levothyroxine is also contraindicated for people with uncorrected adrenal insufficiency, as thyroid hormones may cause an acute adrenal crisis by increasing the metabolic clearance of glucocorticoids.

Just last year I went for another checkup and my doctor “changed his mind” he said that I was just a little above the normal numbers for my thyroid levels for that entire year and the year before.

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For one thing, the lab values that are being considered hypothyroid have changed dramatically in the last few years.

Failure to respond appropriately to higher doses of l-T 4 in compliant patients suggests malabsorption due to a known or occult GI disorder that may require further investigation.

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Although this experimental observation cannot be extrapolated to humans without the usual caveats, some studies have reported that low serum FT 3 and significantly higher serum FT 4 levels can be observed in thyroidectomized patients receiving l-T 4 replacement therapy ().

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Sinus bradycardia, low-voltage complexes on an electrocardiogram (ECG), complete heart block, nonspecific ST-T changes, prolongation of the QT interval, and increased QT dispersion, represent frequent findings at the ECG evaluation in patients with severe hypothyroidism.

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